RGS8 is a member of the regulator of G protein
signaling (RGS) family and encodes a protein with a single RGS
domain. Regulator of G protein signaling (RGS) proteins are
regulatory and structural components of G protein-coupled receptor
complexes. They accelerate transit through the cycle of GTP binding
and hydrolysis to GDP, thereby terminating signal transduction, but
paradoxically, also accelerate receptor-stimulated activation.1) Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
Immunogen
This RGS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human RGS8.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.