Application
Immunofluorescence of RPSA in mouse brain tissue with RPSA Antibodyat 20 μg/mL.Application
Immunofluorescence of RPSA in mouse liver tissue with RPSA antibody at 20 μg/mL.Application
Immunohistochemistry of RPSA in mouse brain tissue with RPSA Antibodyat 5 μg/mL.| Product Name | RPSA Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RPSA Antibody: SA, LBP, LRP, p40, 67LR, ICAS, lamR, 37LRP, LAMBR, LAMR1, LRP/LR, LBP/p40, NEM/1CHD4, 40S ribosomal protein SA, 37 kDa laminin receptor precursor |
| Product description | The 40S ribosomal protein SA (RPSA) is a high-affinity, non-integrin family, laminin receptor, also known as 67 kDa laminin receptor or 37 kDa laminin receptor precursor (37LRP) (1). Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes and have been implicated in a variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis (2). RPSA is overexpressed in multiple types of cancers and has recently been shown to act as a cancer-specific death receptor (3).1) Jackers P, Minoletti F, Belotti D, et al. Isolation from a multigene family of the active human gene of the metastasis-associated 67kDa laminin binding protein 37LRP/p40 at chromosome 3p21.3. Oncogene 1996; 13:495-503. |
| Immunogen | RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA. The immunogen is located within amino acids 190 - 240 of RPSA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHC-P |
| RPSA antibody can be used for detection of RPSA by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RPSA |
|---|---|
| Alternative Names | RPSA Antibody: SA LBP LRP p40 67LR ICAS lamR 37LRP LAMBR LAMR1 LRP/LR LBP/p40 NEM/1CHD4 40S ribosomal protein SA 37 kDa laminin receptor precursor |
| Molecular Weight(MW) | Predicted: 32 kDa Observed: 32 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Pig: (100%), Bovine: (100%), Chicken: (100%), Rat: (100%), Sheep: (100%) |
| Tissue Specificity | RPSA antibody is human, mouse and rat reactive. |
Application
Immunofluorescence of RPSA in mouse brain tissue with RPSA Antibodyat 20 μg/mL.
Application
Immunofluorescence of RPSA in mouse liver tissue with RPSA antibody at 20 μg/mL.
Application
Immunohistochemistry of RPSA in mouse brain tissue with RPSA Antibodyat 5 μg/mL.| Positive Control | 1) Cat. No. 1223 - Caco-2 Cell Lysate |
|---|---|
| Application Notes | RPSA antibody can be used for detection of RPSA by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | RPSA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | RPSA antibody is supplied in PBS containing 0.02% sodium azide. |
