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SERPINE1 Antibody

Catalog Number:OM290932
OM290932
Discount Price
OM290932-100ul
1~2 Week
100ul
OM290932-50ul
50ul
OM290932-20ul
20ul
1~2 Week
Product Profile
Product Name SERPINE1 Antibody
Antibody Type Primary Antibodies
Product description This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.1) Ma, Z., et al. Biochem. Biophys. Res. Commun. 400(4):569-574(2010)
Immunogen This SERPINE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human SERPINE1.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications FACSWB
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SERPINE1
Alternative Names Plasminogen activator inhibitor 1
PAI
PAI-1
Endothelial plasminogen activator inhibitor
Serpin E1
SERPINE1
PAI1
PLANH1
Molecular Weight(MW) 45 kDa
Database Links
Entrez Gene 5054
Protein Accession P05121
Application

Application

Western blot analysis of SERPINE1 using rabbit polyclonal SERPINE1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SERPINE1 gene.

Application

Flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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