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SLC11A1 Antibody

Catalog Number:OM291326
OM291326
Discount Price
OM291326-100ul
1~2 Week
100ul
OM291326-50ul
50ul
OM291326-20ul
20ul
1~2 Week
Product Profile
Product Name SLC11A1 Antibody
Antibody Type Primary Antibodies
Antigen Alias Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1, SLC11A1, LSH, NRAMP, NRAMP1
Product description NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.1) Jin,J., et.al., Zhongguo Dang Dai Er Ke Za Zhi 11 (4), 283-287 (2009)
Immunogen This SLC11A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-276 amino acids from the Central region of human SLC11A1.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IFWB
For WB starting dilution is: 1:1000:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SLC11A1
Alternative Names Natural resistance-associated macrophage protein 1
NRAMP 1
Solute carrier family 11 member 1
SLC11A1
LSH
NRAMP
NRAMP1
Molecular Weight(MW) 60 kDa
Database Links
Entrez Gene 6556
Protein Accession P49279
Application

Application

Western blot analysis of SLC11A1 Antibody in CEM cell line lysates (35ug/lane)

Application

Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
Application Notes For WB starting dilution is: 1:1000:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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