SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.1) Awomoyi, A., (2006) Int. J. Immunogenet. 33 (1), 11-15.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC11A1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
SLC11A1 antibody can be used for detection of SLC11A1 by ELISA at 1:1562500. SLC11A1 antibody can be used for detection of SLC11A1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
SLC11A1 antibody can be used for detection of SLC11A1 by ELISA at 1:1562500. SLC11A1 antibody can be used for detection of SLC11A1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SLC11A1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt