Application
Western blot analysis in mouse liver tissue lysates (35ug/lane).Application
Western Blot at 1:500 dilution + human kidney lysate Lysates/proteins at 20 ug per lane.| Product Name | SOST Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Sclerostin, SOST |
| Product description | Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq].1) van Lierop, A.H., et al. Eur. J. Endocrinol. 163(5):833-837(2010) |
| Immunogen | This SOST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-66 amino acids from the N-terminal region of human SOST. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:500: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SOST |
|---|---|
| Alternative Names | Sclerostin SOST |
| Molecular Weight(MW) | 24 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine |
Application
Western blot analysis in mouse liver tissue lysates (35ug/lane).
Application
Western Blot at 1:500 dilution + human kidney lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:500: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
