Application
Western blot analysis of SPPL3 using rabbit polyclonal SPPL3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2).| Product Name | SPPL3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Signal peptide peptidase-like 3, SPP-like 3, 3423-, Intramembrane protease 2, IMP-2, Presenilin homologous protein 1, PSH1, Presenilin-like protein 4, SPPL3, IMP2, PSL4 |
| Product description | Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.1) Grigorenko, A.P., et al., Biochemistry Mosc. 67(7):826-835 (2002). |
| Immunogen | This SPPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the N-terminal region of human SPPL3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | SPPL3 |
|---|---|
| Alternative Names | Signal peptide peptidase-like 3 SPP-like 3 3423- Intramembrane protease 2 IMP-2 Presenilin homologous protein 1 PSH1 Presenilin-like protein 4 SPPL3 IMP2 PSL4 |
| Molecular Weight(MW) | 43 kDa |
Application
Western blot analysis of SPPL3 using rabbit polyclonal SPPL3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
