Application
Western blot analysis in mouse spleen cell line lysates (35ug/lane).Application
SYNE3 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hodgkin lymphoma followed by peroxidase conjugation of the secondary antibody and DAB staining.| Product Name | SYNE3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Nesprin-3, Nuclear envelope spectrin repeat protein 3, SYNE3, C14orf49 |
| Product description | Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.1) Nery, F.C., et al. J. Cell. Sci. 121 (PT 20), 3476-3486 (2008) : |
| Immunogen | This SYNE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 852-880 amino acids from the C-terminal region of human SYNE3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SYNE3 |
|---|---|
| Alternative Names | Nesprin-3 Nuclear envelope spectrin repeat protein 3 SYNE3 C14orf49 |
| Molecular Weight(MW) | 112 kDa |
Application
Western blot analysis in mouse spleen cell line lysates (35ug/lane).
Application
SYNE3 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hodgkin lymphoma followed by peroxidase conjugation of the secondary antibody and DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
