Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.Application
Antibody used in IHC on Human Thymus at 5 ug/ml.Application
Antibody used in WB on Hum. Fetal Muscle at 1 ug/ml.| Product Name | TARDBP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TARDBP, TDP-43, ALS10 |
| Product description | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Kabashi, E., (2008) Nat. Genet. 40 (5), 572-574. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TARDBP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TARDBP antibody can be used for detection of TARDBP by ELISA at 1:12500. TARDBP antibody can be used for detection of TARDBP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TARDBP |
|---|---|
| Alternative Names | TARDBP TDP-43 ALS10 |
| Molecular Weight(MW) | 45 kDa |
Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human Thymus at 5 ug/ml.
Application
Antibody used in WB on Hum. Fetal Muscle at 1 ug/ml.| Positive Control | 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate |
|---|---|
| Application Notes | TARDBP antibody can be used for detection of TARDBP by ELISA at 1:12500. TARDBP antibody can be used for detection of TARDBP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TARDBP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
