| Product Name | Thymidylate Synthase Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAD51A, RECA, DNA repair protein RAD51 homolog 1, RAD51 homolog A, HsRAD51, BRCC5, MRMV2, HRAD51, HsRad51, HsT16930 |
| Product description | Thymidylate synthase (TS) is anintracellular enzyme critical for de novosynthesis of DNA. In cancer,expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time. |
| Immunogen | Recombinant human thymidylate synthase produced in E. coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCWB |
| IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | RAD51 |
|---|---|
| Alternative Names | RAD51A RECA DNA repair protein RAD51 homolog 1 RAD51 homolog A HsRAD51 BRCC5 MRMV2 HRAD51 HsRad51 HsT16930 |
| Entrez Gene | 5888 |
|---|---|
| Protein Accession | NP_001157741.1 |
| Application Notes | IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Thymidylate Synthase monoclonal Antibodies can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS |
Data sheet for OM293300