TMEM214 Antibody: Transmembrane protein 214 (TMEM214) is a 77kD membrane protein which is widely expressed at high level. The gene encoding this protein maps to chromosome 2, at 2p23.3 TMEM214 interacts with LSM1, an SM-like protein, forming a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. The detailed function of TMEM214 is still unknown, but a recent study showed that TMEM214 may be used to explore the contribution of human host factors of some infectious diseases such as Dengue fever, West Nile fever and yellow fever. Multiple isoforms of TMEM214 are known to exist.1) Wan D, Gong Y, Qin W, et al. Large-scale cDNA transfection screening for genes related to cancer development and progression. Proc. Natl. Acad. Sci. U S A2004;101:15724-9.
Immunogen
TMEM214 antibody was raised against a 17 amino acid synthetic peptide near the center of human TMEM214. The immunogen is located within amino acids 150 - 200 of TMEM214.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
TMEM214 antibody can be used for detection of TMEM214 by Western blot at 1 - 2 μg/mL.:
Western blot analysis of TMEM214 in rat brain tissue lysate with TMEM214 antibody at (A) 1 and (B) 2 μg/mL.
Positive Control
1) Cat. No. 1463 - Rat Brain Tissue Lysate
Application Notes
TMEM214 antibody can be used for detection of TMEM214 by Western blot at 1 - 2 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
TMEM214 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
TMEM214 Antibody is supplied in PBS containing 0.02% sodium azide.