Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Product Name | TNFRSF11B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFRSF11B, OPG, TR1, OCIF |
| Product description | TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.1) Cross, S.S., et al., (2006) Int. J. Cancer 118 (8), 1901-1908. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF11B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TNFRSF11B antibody can be used for detection of TNFRSF11B by ELISA at 1:312500. TNFRSF11B antibody can be used for detection of TNFRSF11B by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TNFRSF11B |
|---|---|
| Alternative Names | TNFRSF11B OPG TR1 OCIF |
| Molecular Weight(MW) | 46 kDa |
Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | TNFRSF11B antibody can be used for detection of TNFRSF11B by ELISA at 1:312500. TNFRSF11B antibody can be used for detection of TNFRSF11B by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TNFRSF11B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
