TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. TP53BP2 contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. TP53BP2 is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family.1) Ju, H., et al., (2005) Int. J. Cancer 117 (6), 957-960.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP53BP2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
TP53BP2 antibody can be used for detection of TP53BP2 by ELISA at 1:1562500. TP53BP2 antibody can be used for detection of TP53BP2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
TP53BP2 antibody can be used for detection of TP53BP2 by ELISA at 1:1562500. TP53BP2 antibody can be used for detection of TP53BP2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TP53BP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.