Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2, TP53BP2, ASPP2, BBP
Product description
TP53BP2 is a member of the ASPP
(apoptosis-stimulating protein of p53) family of p53 interacting
proteins. The protein contains four ankyrin repeats and an SH3
domain involved in protein-protein interactions. It is localized to
the perinuclear region of the cytoplasm, and regulates apoptosis
and cell growth through interactions with other regulatory
molecules including members of the p53 family. Multiple transcript
variants encoding different isoforms have been found for this gene.1) Rose, J. Phd, et al. Mol. Med. (2010) In press :
Immunogen
This TP53BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human TP53BP2.
Apoptosis-stimulating of p53 protein 2 Bcl2-binding protein Bbp Renal carcinoma antigen NY-REN-51 Tumor suppressor p53-binding protein 2 53BP2 p53-binding protein 2 p53BP2 TP53BP2 ASPP2 BBP
Western blot analysis in T47D cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.