| Gene Symbol |
TP53BP2
|
| Gene Synonyms |
BBP 53BP2 ASPP2 P53BP2 PPP1R13A |
| Gene Full Name |
tumor protein p53 binding protein 2 |
| Gene Summary |
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names |
53BP2 Apoptosis stimulating of p53 protein 2 Apoptosis stimulating protein of p53 2 Apoptosis-stimulating of p53 protein 2 ASPP2 ASPP2_HUMAN BBP Bcl2 binding protein Bcl2-binding protein NY REN 51 antigen p53 binding protein 2 p53-binding protein 2 p53BP2 PPP1R13A Renal carcinoma antigen NY-REN-51 Tp53bp2 Tumor protein p53 binding protein 2 Tumor suppressor p53 binding protein 2 Tumor suppressor p53-binding protein 2 |
| Molecular Weight(MW) |
126 kDa |
| Cellular Localization |
Cytoplasm, Nucleus. |