Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.| Product Name | TRDMT1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRDMT1, DNMT2, M.HsaIIP, PuMet, RNMT1, DMNT2, PUMET, MHSAIIP |
| Product description | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.1) Matakidou, A., (2007) Br. J. Cancer 97 (2), 247-252. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRDMT1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| TRDMT1 antibody can be used for detection of TRDMT1 by ELISA at 1:312500. TRDMT1 antibody can be used for detection of TRDMT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TRDMT1 |
|---|---|
| Alternative Names | TRDMT1 DNMT2 M.HsaIIP PuMet RNMT1 DMNT2 PUMET MHSAIIP |
| Molecular Weight(MW) | 44 kDa |
Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate |
|---|---|
| Application Notes | TRDMT1 antibody can be used for detection of TRDMT1 by ELISA at 1:312500. TRDMT1 antibody can be used for detection of TRDMT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TRDMT1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
