Application
Western blot analysis of TROP2 antibody in HL60 cell line lysates (35ug/lane)Application
Formalin-fixed and paraffin-embedded human prostate carcinoma with TROP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Product Name | TROP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1, TACSTD2, GA733-1, M1S1, TROP2 |
| Product description | TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.1) Goldstein,A.S., Proc. Natl. Acad. Sci. U.S.A. 105 (52), 20882-20887 (2008) |
| Immunogen | This TROP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human TROP2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | TACSTD2 |
|---|---|
| Alternative Names | Tumor-associated calcium signal transducer 2 Cell surface glycoprotein Trop-2 Membrane component chromosome 1 surface marker 1 Pancreatic carcinoma marker protein GA733-1 TACSTD2 GA733-1 M1S1 TROP2 |
| Molecular Weight(MW) | 36 kDa |
Application
Western blot analysis of TROP2 antibody in HL60 cell line lysates (35ug/lane)
Application
Formalin-fixed and paraffin-embedded human prostate carcinoma with TROP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
