TRPV1 Antibody: TRPV1 is a receptor for capsaicin, the main pungent ingredient in hot chili peppers, and elicits a sensation of burning pain by selectively activating sensory neurons. TRPV1 is a non-selective cation channel that is structurally related to members of the TRP family of ion channels such as TRPC3 and TRPC6. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.1) Eid SR and Cortright DN. Transient receptor potential channels on sensory nerves. Handb. Exp. Pharmacol. 2009; 194:261-81.
Immunogen
Rabbit polyclonal TRPV1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TRPV1. The immunogen is located within the last 50 amino acids of TRPV1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
TRPV1 antibody can be used for detection of TRPV1 by Western blot at 1 - 2 μg/mL.