Application
Immunohistochemistry staining of XCR1 in spleen tissue using XCR1 Antibody.| Product Name | XCR1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | XCR1, CCXCR1, Chemokine (C motif) receptor 1, Chemokine XC receptor 1, G protein-coupled receptor 5, GPR5, Lptn receptor, Lymphotactin receptor, XC chemokine receptor 1, G-protein coupled receptor 5 |
| Product description | CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease. |
| Immunogen | XCR1 antibody was raised against a peptide located in the 3rd extracellular domain of XCR1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| XCR1 antibody can be used in immunohistochemistry starting at 5 μg/mL, and immunofluorescence.: |
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| Species Reactivity | GibbonGorillaHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | XCR1 |
|---|---|
| Alternative Names | XCR1 CCXCR1 Chemokine (C motif) receptor 1 Chemokine XC receptor 1 G protein-coupled receptor 5 GPR5 Lptn receptor Lymphotactin receptor XC chemokine receptor 1 G-protein coupled receptor 5 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of XCR1 in spleen tissue using XCR1 Antibody.| Application Notes | XCR1 antibody can be used in immunohistochemistry starting at 5 μg/mL, and immunofluorescence.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | XCR1 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
