The protein encoded by this gene is a chemokine receptor
belonging to the G protein-coupled receptor superfamily. The family
members are characterized by the presence of 7 transmembrane
domains and numerous conserved amino acids. This receptor is most
closely related to RBS11 and the MIP1-alpha/RANTES receptor. It
transduces a signal by increasing the intracellular calcium ions
level. The viral macrophage inflammatory protein-II is an
antagonist of this receptor and blocks signaling. Two alternatively
spliced transcript variants encoding the same protein have been
found for this gene.1) Yamazaki, C., et al. Biochem. Biophys. Res. Commun. 397(4):756-761(2010)
Immunogen
This XCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-333 amino acids from the C-terminal region of human XCR1.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.