Application
Immunohistochemistry staining of XRCC5 in brain cortex tissue using XRCC5 monoclonal Antibody.| Product Name | XRCC5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | XRCC5, 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, G22P2, KARP-1, Ku autoantigen, 80kDa, NFIV, KARP1, Ku86, KUB2, TLAA, Nuclear factor IV, KU80, Thyroid-lupus autoantigen |
| Product description | Originally identified as an autoantigen, the Ku protein are nuclear proteins found in eukaryotes. They exist as a heterodimer consisiting of Ku 70 and Ku 80, migrating at approximately 70 and 80 kDa respectively. They bind to DNA ends at double strand breaks. The Ku proteins interact with the DNA-dependent protein kinase (DNA-PK) and participate in the targeting of DNA-PK to DNA. The Ku proteins may participate in numerous cellular processes, including DNA repair and replication, cell signalling, cell proliferation, transcriptional activation and apoptosis. |
| Immunogen | XRCC5 monoclonal antibody was raised against recombinant antigen containing the amino terminal portion of XRCC5 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| XRCC5 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | XRCC5 |
|---|---|
| Alternative Names | XRCC5 86 kDa subunit of Ku antigen CTC85 CTCBF DNA repair protein XRCC5 G22P2 KARP-1 Ku autoantigen 80kDa NFIV KARP1 Ku86 KUB2 TLAA Nuclear factor IV KU80 Thyroid-lupus autoantigen |
Application
Immunohistochemistry staining of XRCC5 in brain cortex tissue using XRCC5 monoclonal Antibody.| Application Notes | XRCC5 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | XRC5 antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS. |
