Application
Immunohistochemistry staining of XRCC6 in testis tissue using XRCC6 monoclonal Antibody.| Product Name | XRCC6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | XRCC6, 5-dRP lyase Ku70, 70 kDa subunit of Ku antigen, CTCBF, DNA repair protein XRCC6, D22S671, D22S731, G22P1, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Thyroid-lupus autoantigen p70, TLAA, CTC75, KU70, ML8, Thyroid-lupus autoantigen |
| Product description | Originally identified as an autoantigen, the Ku protein are nuclear proteins found in eukaryotes. They exist as a heterodimer consisiting of Ku 70 and Ku 80, migrating at approximately 70 and 80 kDa respectively. They bind to DNA ends at double strand breaks. The Ku proteins interact with the DNA-dependent protein kinase (DNA-PK) and participate in the targeting of DNA-PK to DNA. The Ku proteins may participate in numerous cellular processes, including DNA repair and replication, cell signalling, cell proliferation, transcriptional activation and apoptosis. |
| Immunogen | XRCC6 monoclonal antibody was raised against recombinant antigen containing the amino terminal portion of XRCC6 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| XRCC6 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | XRCC6 |
|---|---|
| Alternative Names | XRCC6 5-dRP lyase Ku70 70 kDa subunit of Ku antigen CTCBF DNA repair protein XRCC6 D22S671 D22S731 G22P1 Ku autoantigen 70kDa Ku autoantigen p70 subunit Thyroid-lupus autoantigen p70 TLAA CTC75 KU70 ML8 Thyroid-lupus autoantigen |
Application
Immunohistochemistry staining of XRCC6 in testis tissue using XRCC6 monoclonal Antibody.| Application Notes | XRCC6 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store XRC6 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, pH 7.2. No preservatives added. |
