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CD44 [A7-1]

Catalog Number:OM626710
OM626710
Discount Price
OM626710-100ul
1~2 Week
100ul
OM626710-50ul
50ul
1~2 Week
Product Profile
Product Name CD44 [A7-1]
Antibody Type Primary Antibodies
Antigen Alias LHR antibody BA-1 antibody CD 44 antibody CD44 antibody CD44 antigen antibody CD44 molecule (Indian blood group) antibody CD44 molecule antibody CD44_HUMAN antibody CDw44 antibody Cell surface glycoprotein CD44 antibody chondroitin sulfate proteoglycan 8 antibody CSPG8 antibody ECMR-III antibody Epican antibody Extracellular matrix receptor III antibody GP90 lymphocyte homing/adhesion receptor antibody HCELL antibody hematopoietic cell E- and L-selectin ligand antibody Heparan sulfate proteoglycan antibody Hermes antigen antibody homing function and Indian blood group system antibody HSA antibody HUTCH-I antibody HUTCH1 antibody Hyaluronate receptor antibody IN antibody INLU-related p80 Glycoprotein antibody MC56 antibody MDU2 antibody MDU3 antibody MGC10468 antibody MIC4 antibody MUTCH1 antibody PGP-1 antibody PGP-I antibody PGP1 antibody Phagocytic glycoprotein 1 antibody Phagocytic glycoprotein I antibody Soluble CD44 antibody
Product description CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including lymphocyte homing and tumor-cell metastasis. It mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA), and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is highly polymorphic, possesses a number of alternative splice variants and undergoes extensive post-translational modifications.
Immunogen peptide
Key Feature
Clonality Monoclonal
Isotype IgM
Host Species Mouse
Tested Applications WBIHCFC
WB:1:500-1:1,000
IHC:1:200
FC:1:100-1:200
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names LHR antibody BA-1 antibody CD 44 antibody CD44 antibody CD44 antigen antibody CD44 molecule (Indian blood group) antibody CD44 molecule antibody CD44_HUMAN antibody CDw44 antibody Cell surface glycoprotein CD44 antibody chondroitin sulfate proteoglycan 8 antibody CSPG8 antibody ECMR-III antibody Epican antibody Extracellular matrix receptor III antibody GP90 lymphocyte homing/adhesion receptor antibody HCELL antibody hematopoietic cell E- and L-selectin ligand antibody Heparan sulfate proteoglycan antibody Hermes antigen antibody homing function and Indian blood group system antibody HSA antibody HUTCH-I antibody HUTCH1 antibody Hyaluronate receptor antibody IN antibody INLU-related p80 Glycoprotein antibody MC56 antibody MDU2 antibody MDU3 antibody MGC10468 antibody MIC4 antibody MUTCH1 antibody PGP-1 antibody PGP-I antibody PGP1 antibody Phagocytic glycoprotein 1 antibody Phagocytic glycoprotein I antibody Soluble CD44 antibody
Molecular Weight(MW) 80 kDa
Cellular Localization Cell membrane
Database Links
SwissProt ID P16070
Application

Application

Fig1: Western blot analysis of CD44 on different cell lysates using anti- CD44 antibody at 1/500 dilution. Positive control: Line1: HUVEC Line2: HL-60 Line3: Hela Line4:SKOV3

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD44 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using anti-CD44 antibody. Counter stained with hematoxylin.

Application

Fig4: Flow cytometric analysis of Hela cells with CD44 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti mouse IgG (FITC) was used as the secondary antibody.
Positive Control HUVEC, HL-6, Hela, SKOV3, human colon carcinoma tissue, human tonsil tissue.
Application Notes WB:1:500-1:1,000
IHC:1:200
FC:1:100-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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