Application
Fig1: Western blot analysis of KHSRP on Jurkat cell lysate using anti-KHSRP antibody at 1/500 dilution.Application
Fig2: Flow cytometric analysis of HT-29 cells with KHSRP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.| Product Name | KHSRP [A7-B0] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Far upstream element-binding protein 2 antibody FBP2 antibody FUBP2 antibody FUBP2_HUMAN antibody FUSE binding protein 2 antibody FUSE-binding protein 2 antibody KH type splicing regulatory protein (FUSE binding protein 2) antibody KH type splicing regulatory protein antibody KH type-splicing regulatory protein antibody KHSRP antibody KSRP antibody p75 antibody |
| Product description | Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs. |
| Immunogen | Synthetic peptide within human KHSRP aa 600-700. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 2mg/ml |
| Alternative Names | Far upstream element-binding protein 2 antibody FBP2 antibody FUBP2 antibody FUBP2_HUMAN antibody FUSE binding protein 2 antibody FUSE-binding protein 2 antibody KH type splicing regulatory protein (FUSE binding protein 2) antibody KH type splicing regulatory protein antibody KH type-splicing regulatory protein antibody KHSRP antibody KSRP antibody p75 antibody |
|---|---|
| Molecular Weight(MW) | 73 kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of KHSRP on Jurkat cell lysate using anti-KHSRP antibody at 1/500 dilution.
Application
Fig2: Flow cytometric analysis of HT-29 cells with KHSRP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.| Positive Control | Jurkat, HT-29. |
|---|---|
| Application Notes | WB:1:500-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
