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IL18 [AH10-41]

Catalog Number:OM627073
OM627073
Discount Price
OM627073-100ul
1~2 Week
100ul
OM627073-50ul
50ul
1~2 Week
Product Profile
Product Name IL18 [AH10-41]
Antibody Type Primary Antibodies
Antigen Alias Iboctadekin antibody IFN gamma inducing factor antibody IFN-gamma-inducing factor antibody IGIF antibody IL 1 gamma antibody IL 18 antibody IL 1g antibody IL-1 gamma antibody IL-18 antibody IL1 gamma antibody IL18 antibody IL18 protein antibody IL18_HUMAN antibody IL1F4 antibody IL1g antibody IL1gamma antibody ILIF4 antibody Interferon gamma inducing factor antibody Interferon gamma-inducing factor antibody Interleukin 1 gamma antibody Interleukin 18 (interferon-gamma-inducing factor) antibody Interleukin 18 antibody Interleukin-1 gamma antibody Interleukin-18 antibody Interleukin18 antibody MGC12320 antibody
Product description Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-g production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin's disease cell lines, and does not bind IL-1α or IL-1β. The association of IL-18 to IL-18R leads to activation of NFκB. At present two subunits of IL-18R have been characterized: IL-18Rα and IL-18Rβ. IL-18Rα has been described as the ligand-binding chain and IL-18Rβ as the signal-transduction chain.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications ICC/IFWBICCIHC
WB:1:1,000 ICC
Species Reactivity HumanMouse
Concentration 2mg/ml
Target Information
Alternative Names Iboctadekin antibody IFN gamma inducing factor antibody IFN-gamma-inducing factor antibody IGIF antibody IL 1 gamma antibody IL 18 antibody IL 1g antibody IL-1 gamma antibody IL-18 antibody IL1 gamma antibody IL18 antibody IL18 protein antibody IL18_HUMAN antibody IL1F4 antibody IL1g antibody IL1gamma antibody ILIF4 antibody Interferon gamma inducing factor antibody Interferon gamma-inducing factor antibody Interleukin 1 gamma antibody Interleukin 18 (interferon-gamma-inducing factor) antibody Interleukin 18 antibody Interleukin-1 gamma antibody Interleukin-18 antibody Interleukin18 antibody MGC12320 antibody
Molecular Weight(MW) 22 kDa
Cellular Localization Secreted.
Database Links
SwissProt ID Q14116 P70380
Application

Application

Fig1: ICC staining IL18 in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig2: ICC staining IL18 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: ICC staining IL18 in PC-12 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IL18 Tubulin antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IL18 antibody. Counter stained with hematoxylin.
Positive Control A431, PC-12, Hela, human tonsil tissue, human spleen tissue.
Application Notes WB:1:1,000 ICC
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Stable for 12 months from date of receipt.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.06% Sodium Azide.
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