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L-FABP [AH59-31]

Catalog Number:OM627085
OM627085
Discount Price
OM627085-100ul
1~2 Week
100ul
OM627085-50ul
50ul
1~2 Week
Product Profile
Product Name L-FABP [AH59-31]
Antibody Type Primary Antibodies
Antigen Alias FABP 1 antibody FABP1 antibody FABPL antibody FABPL_HUMAN antibody Fatty Acid Binding Protein 1 antibody Fatty acid binding protein 1 liver antibody Fatty Acid Binding Protein antibody Fatty acid-binding protein 1 antibody Fatty acid-binding protein antibody Fatty acid-binding protein liver antibody L FABP antibody L-FABP antibody liver antibody Liver-type fatty acid-binding protein antibody
Product description Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). Liver-specific FABP (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors and is required for cholesterol synthesis and metabolism.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications ICC/IFWBICCIHC
WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
ELISA:1:5,000-1:10,000
Species Reactivity HumanMouse
Concentration 2mg/ml
Target Information
Alternative Names FABP 1 antibody FABP1 antibody FABPL antibody FABPL_HUMAN antibody Fatty Acid Binding Protein 1 antibody Fatty acid binding protein 1 liver antibody Fatty Acid Binding Protein antibody Fatty acid-binding protein 1 antibody Fatty acid-binding protein antibody Fatty acid-binding protein liver antibody L FABP antibody L-FABP antibody liver antibody Liver-type fatty acid-binding protein antibody
Molecular Weight(MW) 14 kDa
Cellular Localization Cytoplasm.
Database Links
SwissProt ID P07148 P12710
Application

Application

Fig1: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-L-FABP antibody. Counter stained with hematoxylin.

Application

Fig7: ICC staining L-FABP in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig8: ICC staining L-FABP in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig9: ICC staining L-FABP in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Positive Control 293T, HepG2, A431, human liver cancer tissue, human liver tissue, human kidney tissue, mouse kidney tissue, human colon cancer tissue, mouse kidney tissue.
Application Notes WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
ELISA:1:5,000-1:10,000
Additional Information
Form Liquid
Storage Instructions Store at -20 ℃. Stable for 12 months from date of receipt.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.09% Sodium Azide.
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