Application
Fig1: Western blot analysis of CHRNA2 on human CHRNA2 recombinant protein using anti-CHRNA2 antibody at 1/1,000 dilution.Application
Fig2: Western blot analysis of CHRNA2 on HEK293 (1) and CHRNA2-hIgGFc transfected HEK293 (2) cell lysate using anti-CHRNA2 antibody at 1/1,000 dilution.Application
Fig3: Western blot analysis of CHRNA2 on different cell lysate using anti-CHRNA2 antibody at 1/1,000 dilution. Positive control： Line1: SK-N-SH Line2: SH-SY5Y Line3: Membrane protein lysate of C6 Line4: SW480| Product Name | CHRNA2 [H9-G12] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ACHA2_HUMAN antibody AChR antibody Cholinergic receptor nicotinic alpha 2 antibody Chrna2 antibody Neuronal acetylcholine receptor protein subunit alpha 2 antibody Neuronal acetylcholine receptor subunit alpha-2 antibody |
| Product description | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNA2 are the cause of nocturnal frontal lobe epilepsy type 4 (ENFL4). ENFL4 is an autosomal dominant epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500-1:2,000 |
|
| Species Reactivity | HumanRat |
| Concentration | 2mg/ml |
| Alternative Names | ACHA2_HUMAN antibody AChR antibody Cholinergic receptor nicotinic alpha 2 antibody Chrna2 antibody Neuronal acetylcholine receptor protein subunit alpha 2 antibody Neuronal acetylcholine receptor subunit alpha-2 antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| Cellular Localization | Cell junction, Cell membrane |
| SwissProt ID | Q15822 |
|---|
Application
Fig1: Western blot analysis of CHRNA2 on human CHRNA2 recombinant protein using anti-CHRNA2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of CHRNA2 on HEK293 (1) and CHRNA2-hIgGFc transfected HEK293 (2) cell lysate using anti-CHRNA2 antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of CHRNA2 on different cell lysate using anti-CHRNA2 antibody at 1/1,000 dilution. Positive control： Line1: SK-N-SH Line2: SH-SY5Y Line3: Membrane protein lysate of C6 Line4: SW480| Positive Control | Human CHRNA2 recombinant protein, CHRNA2-hIgGFc transfected HEK293 cell lysate, SK-N-SH, SH-SY5Y, SW480 cell lysates, membrane protein lysate of C6. |
|---|---|
| Application Notes | WB:1:500-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
