Application
Fig1: Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti- Slingshot homolog 1 antibody. Counter stained with hematoxylin.Application
Fig2: Flow cytometric analysis of Hela cells with Slingshot homolog 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Product Name | SLINGSHOT-1L [G9-C11] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AW551225 antibody Coro1c antibody coronin, actin binding protein 1C antibody Gm1394 antibody Gm1395 antibody hSSH-1L antibody mSSH 1L antibody OTTMUSP00000031415 antibody Protein phosphatase Slingshot homolog 1 antibody Slingshot 1 antibody slingshot 1L antibody slingshot homolog 1 antibody slingshot like 1 antibody Slingshot1 antibody SSH 1 antibody SSH 1L antibody SSH-1L antibody SSH-like protein 1 antibody Ssh1 antibody SSH1_HUMAN antibody |
| Product description | Slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | IHCFC |
| IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | AW551225 antibody
Coro1c antibody
coronin actin binding protein 1C antibody Gm1394 antibody Gm1395 antibody hSSH-1L antibody mSSH 1L antibody OTTMUSP00000031415 antibody Protein phosphatase Slingshot homolog 1 antibody Slingshot 1 antibody slingshot 1L antibody slingshot homolog 1 antibody slingshot like 1 antibody Slingshot1 antibody SSH 1 antibody SSH 1L antibody SSH-1L antibody SSH-like protein 1 antibody Ssh1 antibody SSH1_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 116 kDa |
| Cellular Localization | Cytoplasm |
| SwissProt ID | Q8WYL5 |
|---|
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti- Slingshot homolog 1 antibody. Counter stained with hematoxylin.
Application
Fig2: Flow cytometric analysis of Hela cells with Slingshot homolog 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human ovarian cancer tissue, Hela |
|---|---|
| Application Notes | IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
