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IL28A [A4-B9]

Catalog Number:OM627401
OM627401
Discount Price
OM627401-100ul
1~2 Week
100ul
OM627401-50ul
50ul
1~2 Week
Product Profile
Product Name IL28A [A4-B9]
Antibody Type Primary Antibodies
Antigen Alias Cytokine ZCYTO20 antibody IFN-lambda-2 antibody IFNL2 antibody IL-28A antibody IL28A antibody IL28A_HUMAN antibody Interferon lambda 2 antibody Interferon lambda-2 antibody interleukin 28A (interferon, lambda 2) antibody Interleukin 28A antibody Interleukin-28A antibody ZCYTO20 antibody
Product description The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. The interleukins are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. Induced by viral infection and show antiviral activity, IL-28A, IL-28B and IL-29 are closely related genes that form a cytokine gene cluster on human chromosome region mapped to 19q13. IL-28A and IL-28B may play a role in antiviral immunity through up-regulation of MHC class I antigen expression and act as ligands for the heterodimeric class II cytokine receptor composed of Il-10Rβ and IL-28R.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBIHC
WB:1:500-1:2,000
IHC:1:50-1:200
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names Cytokine ZCYTO20 antibody IFN-lambda-2 antibody IFNL2 antibody IL-28A antibody IL28A antibody IL28A_HUMAN antibody Interferon lambda 2 antibody Interferon lambda-2 antibody interleukin 28A (interferon
lambda 2) antibody Interleukin 28A antibody Interleukin-28A antibody ZCYTO20 antibody
Molecular Weight(MW) 22 kDa
Cellular Localization Secreted
Database Links
SwissProt ID Q8IZJ0
Application

Application

Fig1: Western blot analysis of IL28A on human IL28A recombinant protein using anti- IL28A antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of IL28A on HEK293 (1) and IL28A-hIgGFc transfected HEK293 (2) cell lysate using anti- IL28A antibody at 1/1,000 dilution.

Application

Fig3: Western blot analysis of IL28A on SK-Br-3 cell lysate using anti- IL28A antibody at 1/1,000 dilution.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-IL28A antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti-IL28A antibody. Counter stained with hematoxylin.
Positive Control Human IL28A recombinant protein, IL28A-hIgGFc transfected HEK293 cell, SK-Br-3, human brain tissue, human esophageal cancer tissue.
Application Notes WB:1:500-1:2,000
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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