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IL1RAPL1

Catalog Number:OM627479
OM627479
Discount Price
OM627479-100ul
1~2 Week
100ul
OM627479-50ul
50ul
1~2 Week
Product Profile
Product Name IL1RAPL1
Antibody Type Primary Antibodies
Antigen Alias IL 1 RAPL 1 antibody IL 1RAPL 1 antibody IL-1-RAPL-1 antibody IL-1RAPL-1 antibody IL1R8 antibody IL1RAPL 1 antibody IL1RAPL antibody IL1RAPL-1 antibody IL1RAPL1 antibody Interleukin 1 receptor 8 antibody Interleukin 1 receptor accessory protein like 1 antibody Interleukin-1 receptor accessory protein-like 1 antibody IRPL1_HUMAN antibody Mental retardation X linked 10 antibody Mental retardation X linked 21 antibody Mental retardation X linked 34 antibody MRX 21 antibody MRX 34 antibody MRX10 antibody MRX21 antibody MRX34 antibody Oligophrenin 4 antibody Oligophrenin-4 antibody Oligophrenin4 antibody OPHN 4 antibody OPHN4 antibody Three immunoglobulin domain containing IL 1 receptor related 2 antibody Three immunoglobulin domain-containing IL-1 receptor-related 2 antibody TIGIRR 2 antibody TIGIRR-2 antibody TIGIRR2 antibody X linked interleukin 1 receptor accessory protein like 1 antibody X-linked interleukin-1 receptor accessory protein-like 1 antibody
Product description May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBICCFC
WB:1:500-1:2,000
ICC:1:50-1:200
FC:1:100-1:200
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names IL 1 RAPL 1 antibody IL 1RAPL 1 antibody IL-1-RAPL-1 antibody IL-1RAPL-1 antibody IL1R8 antibody IL1RAPL 1 antibody IL1RAPL antibody IL1RAPL-1 antibody IL1RAPL1 antibody Interleukin 1 receptor 8 antibody Interleukin 1 receptor accessory protein like 1 antibody Interleukin-1 receptor accessory protein-like 1 antibody IRPL1_HUMAN antibody Mental retardation X linked 10 antibody Mental retardation X linked 21 antibody Mental retardation X linked 34 antibody MRX 21 antibody MRX 34 antibody MRX10 antibody MRX21 antibody MRX34 antibody Oligophrenin 4 antibody Oligophrenin-4 antibody Oligophrenin4 antibody OPHN 4 antibody OPHN4 antibody Three immunoglobulin domain containing IL 1 receptor related 2 antibody Three immunoglobulin domain-containing IL-1 receptor-related 2 antibody TIGIRR 2 antibody TIGIRR-2 antibody TIGIRR2 antibody X linked interleukin 1 receptor accessory protein like 1 antibody X-linked interleukin-1 receptor accessory protein-like 1 antibody
Molecular Weight(MW) 80 kDa
Cellular Localization Cell membrane. Cytoplasm.
Database Links
SwissProt ID Q9NZN1
Application

Application

Fig1: Western blot analysis of IL1RAPL1 on ?human IL1RAPL1 recombinant protein using anti-IL1RAPL1 antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of IL1RAPL1 on HEK293 (1) and IL1RAPL1-hIgGFc transfected HEK293 (2) cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution.

Application

Fig3: Western blot analysis of IL1RAPL1 on different cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution. Positive control: Lane1: A431 Lane2: SK-Hep-1 Lane3: HL-7702

Application

Fig4:ICC staining IL1RAPL1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig5: Flow cytometric analysis of Hela cells with IL1RAPL1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive Control Human IL1RAPL1 recombinant protein, IL1RAPL1-hIgGFc transfected HEK293 cell lysate, A431, SK-Hep-1, HL-7702, Hela.
Application Notes WB:1:500-1:2,000
ICC:1:50-1:200
FC:1:100-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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