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TWIST2 [D9-A11]

Catalog Number:OM627533
OM627533
Discount Price
OM627533-100ul
1~2 Week
100ul
OM627533-50ul
50ul
1~2 Week
Product Profile
Product Name TWIST2 [D9-A11]
Antibody Type Primary Antibodies
Antigen Alias bHLHa39 antibody Class A basic helix-loop-helix protein 39 antibody Dermis expressed protein 1 antibody Dermis-expressed protein 1 antibody DERMO 1 antibody Dermo-1 antibody DERMO1 antibody MGC117334 antibody Twist 2 antibody Twist homolog 2 (Drosophila) antibody Twist homolog 2 antibody Twist related bHLH protein Dermo1 antibody Twist related protein 2 antibody Twist-related protein 2 antibody Twist2 antibody TWST2_HUMAN antibody
Product description Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WB
WB:1:500-1:2,000
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names bHLHa39 antibody Class A basic helix-loop-helix protein 39 antibody Dermis expressed protein 1 antibody Dermis-expressed protein 1 antibody DERMO 1 antibody Dermo-1 antibody DERMO1 antibody MGC117334 antibody Twist 2 antibody Twist homolog 2 (Drosophila) antibody Twist homolog 2 antibody Twist related bHLH protein Dermo1 antibody Twist related protein 2 antibody Twist-related protein 2 antibody Twist2 antibody TWST2_HUMAN antibody
Molecular Weight(MW) 18 kDa
Cellular Localization Nucleus. Cytoplasm.
Database Links
SwissProt ID Q8WVJ9
Application

Application

Fig1: Western blot analysis of TWIST2 on human TWIST2 recombinant protein using anti-TWIST2 antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of TWIST2 on HEK293 (1) and TWIST2-hIgGFc transfected HEK293 (2) cell lysate using anti-TWIST2 antibody at 1/1,000 dilution.
Positive Control Human TWIST2 recombinant protein, TWIST2-hIgGFc transfected HEK293 cell lysate.
Application Notes WB:1:500-1:2,000
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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