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ADAMTS1 [E6-C12]
Catalog Number:OM627552
OM627552
Discount Price
OM627552-100ul
1~2 Week
100ul
OM627552-50ul
50ul
1~2 Week
Product Profile
Product Name ADAMTS1 [E6-C12]
Antibody Type Primary Antibodies
Antigen Alias A disintegrin and metalloproteinase with thrombospondin motifs 1 antibody ADAM-TS 1 antibody ADAM-TS1 antibody ADAMTS 1 antibody ADAMTS antibody ADAMTS-1 antibody Adamts1 antibody ATS1_HUMAN antibody C3 C5 antibody KIAA1346, antibody METH 1 antibody METH-1 antibody
Product description ADAMTS-1, also known as METH-1, C3-C5 and KIAA1346, and the related protein ADAMTS-8, also known as METH-2 and FLJ41712, represent a new family of proteins with metalloprotease, disintegrin and Thrombospondin domains. ADAMTS-1 and ADAMTS-2 are secreted and proteolytically processed proteins that are 51.7% identical but display different, non-overlapping patterns of expression in tissues and cultured celllines. Both ADAMTS proteins have been shown to be more active than Thrombospondin-1 or endostatin in preventing angiogenesis in a cornea pocket model, and both may have application for the inhibition of new blood vessel formation in a range of tumor types. The spacer region and the Thrombospondin type I motifs in the carboxy-terminus of ADAMTS-1 are important for anchoring ADAMTS-1 to the extracellular matrix.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBFC
WB:1:500
FC:1:50-1:100
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names A disintegrin and metalloproteinase with thrombospondin motifs 1 antibody ADAM-TS 1 antibody ADAM-TS1 antibody ADAMTS 1 antibody ADAMTS antibody ADAMTS-1 antibody Adamts1 antibody ATS1_HUMAN antibody C3 C5 antibody KIAA1346
antibody METH 1 antibody METH-1 antibody
Molecular Weight(MW) 80 kDa
Cellular Localization Secreted.
Database Links
SwissProt ID Q9UHI8
Application

Application

Fig1: Western blot analysis of ADAMTS1 on human ADAMTS1 recombinant protein using anti-ADAMTS1 antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of ADAMTS1 on HEK293 (1) and ADAMTS1-hIgGFc transfected HEK293 (2) cell lysate using anti-ADAMTS1 antibody at 1/1,000 dilution.

Application

Fig3: Western blot analysis of ADAMTS1 on Hela cell lysate using anti-ADAMTS1 antibody at 1/1,000 dilution.

Application

Fig4: Flow cytometric analysis of Hela cells with ADAMTS1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

Application

Fig5: Flow cytometric analysis of K562 cells with ADAMTS1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive Control Human ADAMTS1 recombinant protein, ADAMTS1-hIgGFc transfected HEK293 cell lysate, Hela cell lysate, Hela, K562.
Application Notes WB:1:500
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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