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CD7 [F8-D4]

Catalog Number:OM627591
OM627591
Discount Price
OM627591-100ul
1~2 Week
100ul
OM627591-50ul
50ul
1~2 Week
Product Profile
Product Name CD7 [F8-D4]
Antibody Type Primary Antibodies
Antigen Alias CD7 antibody CD7 antigen (p41) antibody CD7 antigen antibody CD7 molecule antibody CD7_HUMAN antibody GP40 antibody LEU 9 antibody LEU9 antibody p41 protein antibody T cell antigen CD7 antibody T cell leukemia antigen antibody T cell surface antigen Leu 9 antibody T-cell antigen CD7 antibody T-cell leukemia antigen antibody T-cell surface antigen Leu-9 antibody Tp 40 antibody Tp40 antibody TP41 antibody
Product description CD7 (also designated T cell leukemia antigen) is a type I transmembrane glycoprotein that is expressed on pluripotential hemapoietic cells, most human thymocytes and some peripheral blood T cells. CD7 is a marker for pluripotential stem cell leukemias and T cell acute lymphocytic leukemia. A role for CD7 in the activation of T cells with g/d receptors has been suggested. CD8 T cells from patients infected with HIV-1 displayed profound down-modulation of CD7 expression as compared with healthy subjects. CD7 is among the pan-T-cell antigens down-regulated in acute infectious mononucleosis.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBIHCFC
WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:100-1:200
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names CD7 antibody CD7 antigen (p41) antibody CD7 antigen antibody CD7 molecule antibody CD7_HUMAN antibody GP40 antibody LEU 9 antibody LEU9 antibody p41 protein antibody T cell antigen CD7 antibody T cell leukemia antigen antibody T cell surface antigen Leu 9 antibody T-cell antigen CD7 antibody T-cell leukemia antigen antibody T-cell surface antigen Leu-9 antibody Tp 40 antibody Tp40 antibody TP41 antibody
Molecular Weight(MW) 25 kDa
Cellular Localization Membrane.
Database Links
SwissProt ID P09564
Application

Application

Fig1: Western blot analysis of CD7 on human CD7 recombinant protein using anti-CD7 antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of CD7 on HEK293 (1) and CD7-hIgGFc transfected HEK293 (2) cell lysate using anti-CD7 antibody at 1/1,000 dilution.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-CD7 antibody. Counter stained with hematoxylin.

Application

Fig4: Flow cytometric analysis of Jurkat cells with CD7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive Control Human CD7 recombinant protein, CD7-hIgGFc transfected HEK293 cell lysate, human lung cancer tissue, Jurkat.
Application Notes WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:100-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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