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POU3F2 [B8-H12]
Catalog Number:OM627707
OM627707
Discount Price
OM627707-100ul
1~2 Week
100ul
OM627707-50ul
50ul
1~2 Week
Product Profile
Product Name POU3F2 [B8-H12]
Antibody Type Primary Antibodies
Antigen Alias Brain 2 antibody Brain specific homeobox/POU domain protein 2 antibody Brain-2 antibodyBrain-specific homeobox/POU domain protein 2 antibody BRN 2 antibody Brn-2 antibody BRN2 antibody N Oct 3 antibody N OCT 3 Gene antibody N Oct3 antibody Nervous system specific octamer binding transcription factor antibody Nervous system-specific octamer-binding transcription factor N-Oct-3 antibody OCT 7 antibody Oct-7 antibody OCT7 antibody Octamer Binding Transcription Factor 7 antibody Octamer-binding protein 7 antibody Octamer-binding transcription factor 7 antibody OTF 7 antibody OTF-7 antibody OTF7 antibody PO3F2_HUMAN antibody POU class 3 homeobox 2, antibody POU domain class 3 transcription factor 2 antibody POU domain, class 3, transcription factor 2 antibody Pou3f2 antibody POUF 3 antibody POUF3 antibody Protein Brn 2 antibody
Product description The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU domain proteins. Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WB
WB:1:500-1:2,000
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names Brain 2 antibody Brain specific homeobox/POU domain protein 2 antibody Brain-2 antibodyBrain-specific homeobox/POU domain protein 2 antibody BRN 2 antibody Brn-2 antibody BRN2 antibody N Oct 3 antibody N OCT 3 Gene antibody N Oct3 antibody Nervous system specific octamer binding transcription factor antibody Nervous system-specific octamer-binding transcription factor N-Oct-3 antibody OCT 7 antibody Oct-7 antibody OCT7 antibody Octamer Binding Transcription Factor 7 antibody Octamer-binding protein 7 antibody Octamer-binding transcription factor 7 antibody OTF 7 antibody OTF-7 antibody OTF7 antibody PO3F2_HUMAN antibody POU class 3 homeobox 2
antibody POU domain class 3 transcription factor 2 antibody POU domain
class 3
transcription factor 2 antibody Pou3f2 antibody POUF 3 antibody POUF3 antibody Protein Brn 2 antibody
Molecular Weight(MW) 47 kDa
Cellular Localization Nucleus.
Database Links
SwissProt ID P20265
Application

Application

Fig1: Western blot analysis of POU3F2 on human POU3F2 recombinant protein using anti-POU3F2 antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of POU3F2 on HeLa (1) and SK-N-SH (2) cell lysate using anti-POU3F2 antibody at 1/1,000 dilution.
Positive Control Human POU3F2 recombinant protein, SK-N-SH.
Application Notes WB:1:500-1:2,000
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
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