Application
Fig1: Western blot analysis of CD94 on human CD94 recombinant protein using anti-CD94 antibody at 1/1,000 dilution.Application
Fig2: Flow cytometric analysis of RAJI cells with CD94 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).| Product Name | CD94 [C6-H1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD 94 antibody CD94 antibody CD94 antigen antibody Killer cell lectin like receptor subfamily D member 1 antibody Killer cell lectin-like receptor subfamily D member 1 antibody KLRD 1 antibody KLRD1 antibody KLRD1 protein antibody KLRD1_HUMAN antibody KP 43 antibody KP43 antibody Natural killer cells antigen CD94 antibody NK cell receptor antibody OTTHUMP00000238754 antibody OTTHUMP00000238755 antibody OTTHUMP00000238756 antibody OTTHUMP00000238758 antibody OTTHUMP00000239093 antibody |
| Product description | The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor (3-4). CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ αβ T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:1,000 FC:1:100-1:200 |
|
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | CD 94 antibody CD94 antibody CD94 antigen antibody Killer cell lectin like receptor subfamily D member 1 antibody Killer cell lectin-like receptor subfamily D member 1 antibody KLRD 1 antibody KLRD1 antibody KLRD1 protein antibody KLRD1_HUMAN antibody KP 43 antibody KP43 antibody Natural killer cells antigen CD94 antibody NK cell receptor antibody OTTHUMP00000238754 antibody OTTHUMP00000238755 antibody OTTHUMP00000238756 antibody OTTHUMP00000238758 antibody OTTHUMP00000239093 antibody |
|---|---|
| Molecular Weight(MW) | 21 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | Q13241 |
|---|
Application
Fig1: Western blot analysis of CD94 on human CD94 recombinant protein using anti-CD94 antibody at 1/1,000 dilution.
Application
Fig2: Flow cytometric analysis of RAJI cells with CD94 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).| Positive Control | Human CD94 recombinant protein, RAJI. |
|---|---|
| Application Notes | WB:1:500-1:1,000 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
