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SCGB2A2 [E2-C80]

Catalog Number:OM627735
OM627735
Discount Price
OM627735-100ul
1~2 Week
100ul
OM627735-50ul
50ul
1~2 Week
Product Profile
Product Name SCGB2A2 [E2-C80]
Antibody Type Primary Antibodies
Antigen Alias Mammaglobin 1 antibody Mammaglobin-1 antibody Mammaglobin-A antibody MGB1 antibody Scgb2a2 antibody Secretoglobin family 2A member 2 antibody SG2A2 antibody SG2A2_HUMAN antibody UGB2 antibody
Product description Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustine-binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B (also designated MGB2, lipophilin C, LPHC, UGB3 and SCGB2A2) is a reliable diagnostic marker for breast tumors.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBICCIHCFC
WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:100-1:200
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names Mammaglobin 1 antibody Mammaglobin-1 antibody Mammaglobin-A antibody MGB1 antibody Scgb2a2 antibody Secretoglobin family 2A member 2 antibody SG2A2 antibody SG2A2_HUMAN antibody UGB2 antibody
Molecular Weight(MW) 11 kDa
Cellular Localization Secreted.
Database Links
SwissProt ID Q13296
Application

Application

Fig1: Western blot analysis of Mammaglobin A on human Mammaglobin A recombinant protein using anti- Mammaglobin A antibody at 1/1,000 dilution.

Application

Fig2: ICC staining Mammaglobin A (green) and actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human mammary cancer tissue using anti- Mammaglobin A antibody. Counter stained with hematoxylin.

Application

Fig4: Flow cytometric analysis of SK-BR-3 cells with Mammaglobin A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).
Positive Control Human Mammaglobin A recombinant protein, Hela, human mammary cancer tissue, SK-BR-3.
Application Notes WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:100-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
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