Application
Fig1: Western blot analysis of INHA on mouse spermary tissue lysate using anti-INHA antibody at 1/1,000 dilution.Application
Fig2: ICC staining INHA (green) and actin filaments (red) in PANC-1 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Product Name | INHA [C8-E2] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | A inhibin subunit antibody A inhibin subunit precursor antibody AW55578 antibody IHA antibody inhA antibody INHA_HUMAN antibody Inhibin alpha chain antibody Inhibin alpha chain precursor antibody Inhibin alpha subunit antibody |
| Product description | Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same α subunit, covalently linked to 1 of 2 distinct subunits, β-α or β-β. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor β (TGFβ) superfamily of growth and differentiation factors. TGFβ proteins affect a range of tissues and systems beyond their role in reproduction. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, placenta and, most notably, anterior pituitary. Inhibin α-subunit gene expression is down regulated in human prostate cancer, suggesting a tumor-suppressive role. The human Inhibin α gene maps to chromosome 2q33-q36. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICC |
| WB:1:500-1:1,000 ICC:1:50-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Alternative Names | A inhibin subunit antibody A inhibin subunit precursor antibody AW55578 antibody IHA antibody inhA antibody INHA_HUMAN antibody Inhibin alpha chain antibody Inhibin alpha chain precursor antibody Inhibin alpha subunit antibody |
|---|---|
| Molecular Weight(MW) | 40 kDa |
| Cellular Localization | Secreted. |
Application
Fig1: Western blot analysis of INHA on mouse spermary tissue lysate using anti-INHA antibody at 1/1,000 dilution.
Application
Fig2: ICC staining INHA (green) and actin filaments (red) in PANC-1 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Positive Control | Mouse spermary tissue lysate, PANC-1. |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
