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LPA [B6-H1]

Catalog Number:OM627756
OM627756
Discount Price
OM627756-100ul
1~2 Week
100ul
OM627756-50ul
50ul
1~2 Week
Product Profile
Product Name LPA [B6-H1]
Antibody Type Primary Antibodies
Antigen Alias AK38 antibody Antiangiogenic AK38 protein antibody apo(a) antibody APOA antibody apolipoprotein(a) antibody LP antibody lp(a) antibody LPA antibody
Product description The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBICCIHC
WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names AK38 antibody
Antiangiogenic AK38 protein antibody
apo(a) antibody
APOA antibody
apolipoprotein(a) antibody
LP antibody
lp(a) antibody
LPA antibody
Molecular Weight(MW) 501 kDa
Cellular Localization Extracellular region. Secreted.
Database Links
SwissProt ID P08519
Application

Application

Fig1: Western blot analysis of Lipoprotein a on human Lipoprotein a recombinant protein using anti- Lipoprotein a antibody at 1/1,000 dilution.

Application

Fig2: ICC staining Lipoprotein a (green) and actin filaments (red) in HepG2 cell. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.
Positive Control Human Lipoprotein a recombinant protein, HepG2, human liver cancer tissue, human breast cancer tissue, human rectum cancer tissue.
Application Notes WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
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