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TGFb1 [B2-F6]

Catalog Number:OM627762
OM627762
Discount Price
OM627762-100ul
1~2 Week
100ul
OM627762-50ul
50ul
1~2 Week
Product Profile
Product Name TGFb1 [B2-F6]
Antibody Type Primary Antibodies
Product description The transforming growth factors b (TGFβ) superfamily is composed of numerous growth and differentiation factors, including TGFβ1-3. TGFβs are secreted from cells as latent complexes consisting of mature dimeric growth factor, the latency-associated propeptide (LAP) and a distinct gene product, latent TGFβ binding protein LTBP. Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis. The precursor of TGFβ is cleaved into mature TGFβ and LAP (latency associated peptide). Mature TGFβ remains associated with LAP by non-covalent interactions that block TGFβ from binding to its receptor.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBIHCFC
WB:1:500-1:1,000
IHC:1:100-1:500
FC:1:100-1:200
Species Reactivity Human
Concentration 2mg/ml
Target Information
Molecular Weight(MW) 44 kDa
Cellular Localization Secreted. Extracellular matrix.
Database Links
SwissProt ID P01137
Application

Application

Fig1: Western blot analysis of TGF beta 1 on human TGF beta 1 recombinant protein using anti- TGF beta 1 antibody at 1/1,000 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti- TGF beta 1 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human lymphoid tissue using anti- TGF beta 1 antibody. Counter stained with hematoxylin.

Application

Fig4: Flow cytometric analysis of A549 cells with TGF beta 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive Control Human TGF beta 1 recombinant protein, human lung tissue, human lymphoid tissue, A549.
Application Notes WB:1:500-1:1,000
IHC:1:100-1:500
FC:1:100-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
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