Application
Western blot analysis of KAT6B against human KAT6B (AA: 1186-1318) recombinant protein. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (EM1712-10, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.Application
Western blot analysis of KAT6B against HEK293 (1) and KAT6B (AA: 1186-1318)-hIgGFc transfected HEK293 (2) cell lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (EM1712-10, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.| Product Name | KAT6B [8C8D12] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500-1:2,000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/mL |
| Purification | Unpurified |
| Alternative Names | DKFZp313G1618 antibody FLJ90335 antibody Histone acetyltransferase MORF antibody Histone acetyltransferase MOZ2 antibody Histone acetyltransferase MYST4 antibody KAT 6B antibody KIAA0383 antibody Monocytic leukemia zinc finger protein related factor antibody Monocytic leukemia zinc finger protein-related factor antibody MOZ 2 antibody MOZ antibody MOZ related factor antibody MOZ YBF2/SAS3 SAS2 and TIP60 protein 4 antibody MOZ2 antibody MYST 4 antibody MYST histone acetyltransferase (monocytic leukemia) 4 antibody MYST protein 4 antibody MYST-4 antibody MYST4 antibody MYST4_HUMAN antibody OTTHUMP00000019866 antibody OTTHUMP00000019867 antibody OTTHUMP00000019869 antibody OTTHUMP00000019870 antibody QKF antibody Querkopf antibody SAS2 and TIP60 protein 4 antibody YBF2/SAS3 antibody |
|---|---|
| Molecular Weight(MW) | 231.4kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q8WYB5 |
|---|
Application
Western blot analysis of KAT6B against human KAT6B (AA: 1186-1318) recombinant protein. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (EM1712-10, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.
Application
Western blot analysis of KAT6B against HEK293 (1) and KAT6B (AA: 1186-1318)-hIgGFc transfected HEK293 (2) cell lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (EM1712-10, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.| Positive Control | Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary. |
|---|---|
| Application Notes | WB:1:500-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*PBS with 0.05% sodium azide. |
