Application
Fig1: Western blot analysis of IMP3 on 293T cell lysate using anti-IMP3 antibody at 1/2,000 dilution.Application
Fig2: Flow cytometric analysis of PANC-1 cells with IMP3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.| Product Name | IMP3 [4-C2-5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cancer/testis antigen 98 antibody CT98 antibody DKFZp686F1078 antibody hKOC antibody IF2B3_HUMAN antibody IGF II mRNA binding protein 3 antibody IGF-II mRNA-binding protein 3 antibody IGF2 mRNA binding protein 3 antibody IGF2 mRNA-binding protein 3 antibody IGF2BP3 antibody IMP 3 antibody IMP-3 antibody Insulin like growth factor 2 mRNA binding protein 3 antibody Insulin-like growth factor 2 mRNA-binding protein 3 antibody KH domain containing protein overexpressed in cancer antibody KH domain-containing protein overexpressed in cancer antibody KOC 1 antibody KOC1 antibody VICKZ 3 antibody VICKZ family member 3 antibody VICKZ3 antibody |
| Product description | RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. |
| Immunogen | Recombinant protein within human IMP3 aa 350-650. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:1,000 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Alternative Names | Cancer/testis antigen 98 antibody CT98 antibody DKFZp686F1078 antibody hKOC antibody IF2B3_HUMAN antibody IGF II mRNA binding protein 3 antibody IGF-II mRNA-binding protein 3 antibody IGF2 mRNA binding protein 3 antibody IGF2 mRNA-binding protein 3 antibody IGF2BP3 antibody IMP 3 antibody IMP-3 antibody Insulin like growth factor 2 mRNA binding protein 3 antibody Insulin-like growth factor 2 mRNA-binding protein 3 antibody KH domain containing protein overexpressed in cancer antibody KH domain-containing protein overexpressed in cancer antibody KOC 1 antibody KOC1 antibody VICKZ 3 antibody VICKZ family member 3 antibody VICKZ3 antibody |
|---|---|
| Molecular Weight(MW) | 64kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of IMP3 on 293T cell lysate using anti-IMP3 antibody at 1/2,000 dilution.
Application
Fig2: Flow cytometric analysis of PANC-1 cells with IMP3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.| Positive Control | 293T, PANC-1. |
|---|---|
| Application Notes | WB:1:500-1:1,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
