| Product Name | FH [7F1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) antibody; |
| Product description | The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. |
| Immunogen | Synthetic Peptide of FH |
| Clonality | Monoclonal |
|---|---|
| Host Species | Mouse |
| Tested Applications | WBIHCIF |
| WB:1:3000 IF:1:200 IHC:1:50-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Fumarate hydratase mitochondrial (Fumarase) (EC 4.2.1.2) antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| SwissProt ID | P07954 |
|---|
| Positive Control | Brain,Cajal-Retzius cell,Liver,Uterus, |
|---|---|
| Application Notes | WB:1:3000 IF:1:200 IHC:1:50-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
