| Product Name | NBR1 [7C3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B) antibody; |
| Product description | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21. 1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. |
| Immunogen | Recombinant Protein of NBR1 |
| Clonality | Monoclonal |
|---|---|
| Host Species | Mouse |
| Tested Applications | IFIHC |
| IF:1:50-200 IHC:1:50-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B) antibody |
|---|---|
| Molecular Weight(MW) | 120 kDa |
| SwissProt ID | Q14596 |
|---|
| Positive Control | Bone marrow,Lymph,Ovary,Testis, |
|---|---|
| Application Notes | IF:1:50-200 IHC:1:50-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
