IgG is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. This antibody reacts with kappa-light-chain of human IgG.
Immunogen
Human IgG
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Host Species
Mouse
Tested Applications
WBICC/IF
WB:1:2,000-1:5,000 ELISA:5,000
Species Reactivity
Human
Concentration
2mg/ml
Target Information
Molecular Weight(MW)
25 kDa
Cellular Localization
Serum/ Plasma
Application
Application
Fig: Western blot analysis on huamn IgG using anti-human kappa light chain antibody.