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Neuropilin 1 [A3-D1]

Catalog Number:OM638521
OM638521
Discount Price
OM638521-100ul
1~2 Week
100ul
OM638521-50ul
50ul
1~2 Week
Product Profile
Product Name Neuropilin 1 [A3-D1]
Antibody Type Primary Antibodies
Antigen Alias AI851453 antibody BCTL1 antibody Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody BTCL1 antibody C130005O10Rik antibody FLJ41325 antibody Neto1 antibody NETO1_HUMAN antibody Neuropilin and tolloid like 1 antibody Neuropilin and tolloid-like protein 1 antibody RGD1566269 antibody
Product description The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgM
Host Species Mouse
Tested Applications WBICCIHC
WB:1:1,000-1:10,000
ICC:1:100-1:500
IHC:1:50
Species Reactivity HumanMouse
Concentration 2mg/ml
Target Information
Alternative Names AI851453 antibody BCTL1 antibody Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody BTCL1 antibody C130005O10Rik antibody FLJ41325 antibody Neto1 antibody NETO1_HUMAN antibody Neuropilin and tolloid like 1 antibody Neuropilin and tolloid-like protein 1 antibody RGD1566269 antibody
Molecular Weight(MW) 103 kDa
Cellular Localization Cell membrane
Database Links
SwissProt ID O14786 P97333
Application

Application

Fig1: Western blot analysis on recombinant protein using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).

Application

Fig2:Immunofluorescent staining of Hela cells using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).

Application

Fig3:Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).
Positive Control Hela, mouse brain tissue
Application Notes WB:1:1,000-1:10,000
ICC:1:100-1:500
IHC:1:50
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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