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CCDC51 [A8-F4-D1]

Catalog Number:OM638528
OM638528
Discount Price
OM638528-100ul
1~2 Week
100ul
OM638528-50ul
50ul
1~2 Week
Product Profile
Product Name CCDC51 [A8-F4-D1]
Antibody Type Primary Antibodies
Antigen Alias 5730568A12Rik antibody AI551049 antibody CCD51_HUMAN antibody CCDC51 antibody Coiled coil domain containing 51 antibody Coiled-coil domain-containing protein 51 antibody FLJ12436 antibody RGD1311466 antibody
Product description The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC51 (coiled-coil domain containing 51) is a 411 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding CCDC51 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications WBIHC
WB:1:250~1:1000
IHC:1:20~1:100
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Concentration 2mg/ml
Target Information
Alternative Names 5730568A12Rik antibody AI551049 antibody CCD51_HUMAN antibody CCDC51 antibody Coiled coil domain containing 51 antibody Coiled-coil domain-containing protein 51 antibody FLJ12436 antibody RGD1311466 antibody
Molecular Weight(MW) 46 kDa
Cellular Localization Membrane, nucleus.
Database Links
SwissProt ID Q96ER9
Application

Application

Fig1: Western blot analysis of CCDC51 on recombinant protein using anti-CCDC51 antibody at 1/1,000 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CCDC51 antibody. Counter stained with hematoxylin

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.

Application

Fig8: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.

Application

Fig9: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
Positive Control Recombinant protein, human liver tissue, human lung tissue, human pancreas tissue, human tonsil tissue, human thyroid tissue, human spleen tissue tissue.
Application Notes WB:1:250~1:1000
IHC:1:20~1:100
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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