Application
Fig1: Western blot analysis on human brain tissue lysates using anti-CD80 Mouse mAb (Cat. # M1007-10)Application
Fig2：Immunofluorescent staining of L929 cells using using anti-CD80 Mouse mAb (Cat. # M1007-10).Application
Fig3：Immunohistochemical analysis of paraffin- embedded human brain tissue using using anti-CD80 Mouse mAb (Cat. # M1007-10).| Product Name | CD80/B7-1 [8-E5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CD80/B7-1 is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of B7 to CD28 greatly upregulates the production of multiple lymphokines. B7-1 is a costimulatory molecule for the activation of both CD4+ and CD8+ T lymphocytes that prevents the induction of clonal anergy. Thus, the transfer of B7-1 genes into tumor cells can induce protective immunity and lead to tumor rejection of some tumors in model systems of in vivo tumor growth. |
| Immunogen | peptide |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Host Species | Mouse |
| Tested Applications | WB,ICC,IHC,FC |
| WB:1:500 ICC:1:100-1:200 IHC:1:50 |
|
| Species Reactivity | Human,Mouse |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | Activation B7-1 antigen antibody
B lymphocyte activation antigen B7 antibody
B7 antibody
B7-1 antibody
B7-1 antigen antibody
B7.1 antibody
BB1 antibody
CD28 antigen ligand 1 antibody
CD28LG antibody
CD28LG1 antibody
CD80 antibody
CD80 antigen (CD28 antigen ligand 1 B7-1 antigen) antibody CD80 antigen antibody CD80 molecule antibody CD80_HUMAN antibody Costimulatory factor CD80 antibody costimulatory molecule variant IgV-CD80 antibody CTLA-4 counter-receptor B7.1 antibody LAB7 antibody T-lymphocyte activation antigen CD80 antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| Cellular Localization | cell membrane |
| SwissProt ID | P33681 |
|---|
Application
Fig1: Western blot analysis on human brain tissue lysates using anti-CD80 Mouse mAb (Cat. # M1007-10)
Application
Fig2：Immunofluorescent staining of L929 cells using using anti-CD80 Mouse mAb (Cat. # M1007-10).
Application
Fig3：Immunohistochemical analysis of paraffin- embedded human brain tissue using using anti-CD80 Mouse mAb (Cat. # M1007-10).| Positive Control | human brain, L929 |
|---|---|
| Application Notes | WB:1:500 ICC:1:100-1:200 IHC:1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
