IgG is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. This antibody reacts with kappa-light-chain of human IgG.
Immunogen
Human IgG light chain
Conjugation
HRP
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Host Species
Mouse
Tested Applications
WBICC/IF
WB:1:2,000-1:5,000 ELISA:1:1,000
Species Reactivity
Human
Concentration
2mg/ml
Target Information
Molecular Weight(MW)
25 kDa
Cellular Localization
Serum/ Plasma
Application
Application
Fig1: Representative standard curve using Mouse mAb (Cat. # M1007-11).
Application
Fig2: Western blot analysis on human IgG κchain using anti-Human IgG light chain(kappa chain) conjugated HRP Mouse mAb (Cat. # M1007-11).