Application
Fig1: Western blot analysis on MCF-7 cell lysates using anti-HP-1αMouse mAb (Cat. # M1211-2).Application
Fig2：Immunofluorescent staining of MCF-7 cells using anti-HP-1α Mouse mAb (Cat. # M1211-2).| Product Name | HP1 alpha [B0-1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Antigen p25 antibody CBX5 antibody CBX5_HUMAN antibody CG8409 antibody Chromobox 5 antibody Chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody Chromobox homolog 5 antibody Chromobox protein homolog 5 antibody Epididymis luminal protein 25 antibody HEL25 antibody Heterochromatin protein 1 alpha antibody Heterochromatin protein 1 antibody Heterochromatin protein 1 homolog alpha antibody HP1 alpha antibody HP1 alpha homolog antibody HP1 antibody HP1A antibody HP1Hs alpha antibody Su(var)205 antibody |
| Product description | The family of Heterochromatin Protein 1 (HP1) ("Chromobox Homolog", CBX) are highly conserved adapter proteins, which have important functions in the cell nucleus. These functions include gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level and gene repression by heterochromatization of euchromatin.Three different paralogs of HP1 are found in mammals, HP1α, HP1βand HP1γ. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICC |
| WB:1:5,000 ICC:1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Alternative Names | Antigen p25 antibody
CBX5 antibody
CBX5_HUMAN antibody
CG8409 antibody
Chromobox 5 antibody
Chromobox homolog 5 (HP1 alpha homolog Drosophila) antibody Chromobox homolog 5 antibody Chromobox protein homolog 5 antibody Epididymis luminal protein 25 antibody HEL25 antibody Heterochromatin protein 1 alpha antibody Heterochromatin protein 1 antibody Heterochromatin protein 1 homolog alpha antibody HP1 alpha antibody HP1 alpha homolog antibody HP1 antibody HP1A antibody HP1Hs alpha antibody Su(var)205 antibody |
|---|---|
| Molecular Weight(MW) | 22kDa |
| Cellular Localization | Nucleus |
| SwissProt ID | P45973 |
|---|
Application
Fig1: Western blot analysis on MCF-7 cell lysates using anti-HP-1αMouse mAb (Cat. # M1211-2).
Application
Fig2：Immunofluorescent staining of MCF-7 cells using anti-HP-1α Mouse mAb (Cat. # M1211-2).| Positive Control | MCF-7 |
|---|---|
| Application Notes | WB:1:5,000 ICC:1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
