Application
Fig1: Western blot analysis on mouse heart (1) and human heart (2) lysates using anti-N-Cadherin mouse mAb.Application
Fig2：Immunofluorescent staining of A549 cells using anti-N-Cadherin mouse mAb.Application
Fig3：Immunohistochemical analysis of paraffin- embedded human lung cancer tissue using anti-N-Cadherin mouse mAb.| Product Name | N-Cadherin [A10-4] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CADH2_HUMAN antibody Cadherin 2 antibody Cadherin 2 N cadherin neuronal antibody Cadherin 2 type 1 antibody Cadherin 2 type 1 N cadherin neuronal antibody Cadherin 2, type 1, N-cadherin (neuronal) antibody Cadherin-2 antibody Cadherin2 antibody Calcium dependent adhesion protein neuronal antibody CD325 antibody CD325 antigen antibody CDH2 antibody CDHN antibody CDw325 antibody CDw325 antigen antibody N cadherin 1 antibody N-cadherin antibody NCAD antibody Neural cadherin antibody OTTHUMP00000066304 antibody OTTHUMP00000067378 antibody |
| Product description | The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events. The cadherin subfamily includes N-, P-, B-, and E- cadherins, and other members. Recent studies indicate that cancer cells have up-regulated N-cadherin in addition to loss of E-cadherin. This change in cadherin expression is called the "cadherin switch". N-cadherin cooperates with the FGF receptor, leading to overexpression of MMP-9 and cellular invasion. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Host Species | Mouse |
| Tested Applications | WBICCIHC |
| WB: 1:1,000-1:2,000 ICC: 1:500 IHC: 1:100 |
|
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Alternative Names | CADH2_HUMAN antibody
Cadherin 2 antibody
Cadherin 2 N cadherin neuronal antibody
Cadherin 2 type 1 antibody
Cadherin 2 type 1 N cadherin neuronal antibody
Cadherin 2 type 1 N-cadherin (neuronal) antibody Cadherin-2 antibody Cadherin2 antibody Calcium dependent adhesion protein neuronal antibody CD325 antibody CD325 antigen antibody CDH2 antibody CDHN antibody CDw325 antibody CDw325 antigen antibody N cadherin 1 antibody N-cadherin antibody NCAD antibody Neural cadherin antibody OTTHUMP00000066304 antibody OTTHUMP00000067378 antibody |
|---|---|
| Molecular Weight(MW) | 140 kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P19022 |
|---|
Application
Fig1: Western blot analysis on mouse heart (1) and human heart (2) lysates using anti-N-Cadherin mouse mAb.
Application
Fig2：Immunofluorescent staining of A549 cells using anti-N-Cadherin mouse mAb.
Application
Fig3：Immunohistochemical analysis of paraffin- embedded human lung cancer tissue using anti-N-Cadherin mouse mAb.| Positive Control | A549, human lung cancer tissue, human heart, |
|---|---|
| Application Notes | WB: 1:1,000-1:2,000 ICC: 1:500 IHC: 1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
